Research Portfolio

Propofol on trial for headaches in the Emergency Department setting

Headache is a common and frequently disabling clinical disorder that accounts for nearly 2% of all emergency department presentations. Often patients are experiencing a headache that is not responding to commonly available medications. However, there is no good evidence to support which available hospital medications consistently offer effective pain relief to individuals with these types of refractory headache. Understandably this is a challenging scenario in the emergency department setting for both the patient and physician that often leads to inadequate or unsatisfactory symptom relief. In a few small trials, there has been promising evidence that the medication propofol is potentially…

Principal Investigator: Dr Erik Wood
Amount Awarded: $7,860
Institution:

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A brief psychological intervention to promote recovery after mild traumatic brain injury

Mild traumatic brain injury (mTBI) is a common injury with potentially profound consequences. Although many patients recover within a few days to a few weeks, an estimated 15-40% develop post-concussion syndrome (PCS), which consists of an array of cognitive, emotional, and physical symptoms.(TBI symptoms that persist beyond three months often develop into a chronic, potentially life-long, health problem.) PCS is associated with problems returning to work, social difficulties, higher healthcare utilisation, and poorer quality of life. The mitigation of PCS represents a significant clinical problem. An effective evidence-based early intervention to prevent PCS is sorely needed. There is a growing…

Principal Investigator: Dr Shane Martin
Amount Awarded: $69,657
Institution:

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First aid oxygen treatment of divers with decompression sickness

Decompression sickness (DCS), commonly called the bends, involves formation of gas bubbles in the body following scuba diving. These bubbles can cause a variety of problems, ranging from minor aches and pain, to severe stroke-like symptoms. Providing pre-hospital oxygen therapy at the highest concentration possible provides needed oxygen to body tissues, reduces bubbles and can often relieve symptoms. Oxygen has been shown to reduce the number of hyperbaric treatments a diver with DCS will require so improving pre-hospital oxygen delivery will lead to decreased hospital costs. However, the ideal oxygen delivery system has not been determined. Using new techniques and…

Principal Investigator: Dr Denise Blake
Amount Awarded: $30,003
Institution:

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Evaluating rates of skin colonisation with MRSA or Group A Streptococci

Group A Streptococcal (GAS) is known to be the cause of Acute Rheumatic Fever (ARF) and Chronic Rheumatic Heart Disease (CRHD). Worldwide Community acquired (CA) Methicillin Resistant Staphylococcus Aureus (MRSA) is an increasing problem which has also been identified in Australia since the 1990s. At times, the rates in North West HHS have been as high as 30%. This has implications for both the local HHS and the health system more broadly for patients that then require transfer to other facilities. The purpose of this research is to conduct a snapshot study for the evaluation of rate of skin colonisation…

Principal Investigator: Dr Geoffrey Rofe
Amount Awarded: $68,224
Institution:

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Ketamine versus propofol in sedation of psychiatric patients requiring retrieval

The aeromedical retrieval of acute psychiatric patients is a challenging scenario for the most experienced clinician. This is due to the potential for unpredictable behaviour among these patients, coupled with the inherent dangers of the aviation environment. Chemical restraint is one of the accepted strategies in this environment to ensure patient and crew safety and to minimise patient distress. Benzodiazepines and antipsychotics have been the most commonly employed drugs for chemical restraint, although they are sometimes limited by adverse reactions and inadequate sedation endangering the safety of patient and health care providers. Consequently, there has been increasing interest in drugs…

Principal Investigator: Dr Luke Burman
Amount Awarded: $8,400
Institution:

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