Research Portfolio

Research capacity building: Redcliffe Hospital

Redcliffe Hospital Emergency Department (ED) has a growing research track record and an increasing number of clinical staff engaging in research-related activities. To capitalise on this burgeoning interest, we will funding a dedicated Clinical Research Coordinator to provide active support, coordination and promotion of both current and future research activities. The aim of our endeavour is to establish research as a core element of ED activity, together with education & training, provision of clinical care and maintenance of standards in healthcare. We intend to conduct our future research under the auspices of leaders and champions representing four thematic headings: 1.…

Principal Investigator: A/Prof Douglas Morel
Amount Awarded: $108,440
Institution:

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Assessing Children’s Head Injury: Variation in CT scan use (APHIRST-Gap)

This study will collect information from the records of 3000 children from 30 hospitals presenting after a head injury in 2016 and will interview staff to look at different factors influencing the care provided. APHIRST-Gap is expected to provided crucial information on scan rates and inform strategies, including national guideline development to standardise and improve the care of children with head injury across Australia and New Zealand. Head injury is a common reason children present to Emergency Departments in Australia and New Zealand. While most are minor the important issue for emergency clinicians is to determine whether a particular child…

Principal Investigator: Dr Natalie Phillips
Amount Awarded: $62,749
Institution:

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Preventing chronic pain after whiplash injury

After whiplash injury, half of patients never fully recover. The human and economic cost is enormous, and current mainstay treatments are ineffective. Most recovery, if it occurs, takes place in the first two to three months. This early time period offers a ‘window of opportunity’ to pro-actively intervene and prevent the chronic pain. The Emergency Department (ED) is ideally placed to provide very early intervention. We have shown that upregulation of pain in the central nervous system occurs soon after whiplash injury and predicts poor recovery. We aim to target these central nervous system processes with pregabalin in conjunction with…

Principal Investigator: Professor Gerben Keijzers
Amount Awarded: $83,639
Institution:

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Rapid diagnosis of sepsis in acutely ill children

Life threatening bacterial infections such as sepsis are a leading cause of childhood mortality. International authorities recognise the urgent need for better recognition, diagnosis, and management of children with sepsis. Children in regional and remote settings are at particular risk for late or inaccurate diagnosis resulting in worse outcomes. In this study, we are testing the feasibility, performance, time-to-diagnosis, and cost impact of applying the most advanced genomics-based sepsis diagnostic tools. This could lead to better treatment of infections, reduce unnecessary antibiotic use, shorten hospital length of stay, improve patient outcomes, and allow patients and families to be managed closer…

Principal Investigator: Dr Peter Snelling
Amount Awarded: $100,000
Institution:

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Fibrinogen Early In Severe Trauma in children studY (FEISTY Junior)

Traumatic injuries in children are a leading cause of death and disability in Australia. In high income countries, 40% of child deaths are because of traumatic injuries. Fibrinogen is one of the key clotting factors that need to be replaced in severe traumatic bleeding. Currently, fibrinogen is replaced using cryoprecipitate; a blood product obtained from healthy volunteer donors. This is a precious resource that is stored frozen in the blood bank; it can take a long time to administer and place significant strain on blood banks. Fibrinogen concentrate (FC) is an alternative product used to assist in blood clotting. It…

Principal Investigator: Dr Christa Bell
Amount Awarded: $100,000
Institution:

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