Paced Electrocardiogram Requiring Fast Emergent Coronary Therapy (PERFECT) Study.

Diagnosis of Acute Coronary Occlusion in patients with a Ventricular Paced Rhythm.

Grant ID: EMTR-154R25-2016

Lay Summary

The aim of this study is to assess the performance characteristics of the modified Sgarbossa criteria for diagnosis of ACO in VPR. This is a multi-centre international trial. The number of patients presenting to our Emergency Departments with pacemakers continues to increase. Investigating whether such patients are having a heart attack is challenging. For patients without pacemakers, ECG criteria can be used to identify a subset of patients who are having a heart attack. However, for patients with pacemakers, there are no accurate electrocardiograph (ECG) criteria to diagnose heart attacks.

This research has the potential to identify AMI in patients with VPR and improve Emergency Medical care in a time critical management decision. As such, it will develop emergency medicine research in Queensland and internationally by improving patients care and outcomes. It also will develop education and knowledge that will be recognised worldwide.

Smith et al have derived criteria (modified Sgarbossa’s criteria) for diagnosing heart attack using ECG characteristics in patients with a known abnormal ECG trace. This study will assess the accuracy of the Sgarbossa’s criteria in patients with pacemakers

We will collect data on demographics and ECG criteria for patients with pacemakers who present to the Emergency Department at the Royal Brisbane and Women’s Hospital with potential heart attack. We will then examine the results from the patient’s angiogram. An angiogram is when a contrast is inserted into an artery and images of the hearts blood vessels taken, to see if there is coronary blood vessel occlusion. We will identify whether the ECG criteria of patients with paced rhythms are accurate in identifying patients who did or did not have a coronary blood vessel occlusion on angiogram.

The data will combined with data from multiple sites around the world to help validate ECG criteria for diagnosing heart attack in patients with pacemakers.


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Amount Awarded
$16,866


Program


Grant Scheme


Status
Active


Principal Investigator:
Dr Gary Mitchell


Co Investigators:
Dr Stephen Smith
Dr Kenneth Dodd


Supervisor:
Louise Cullen


Institution



CONTACT US +61 7 3720 5700 info@emfoundation.org.au 2/15 Lang Parade Milton Qld 4064