A Prospective Observational Cohort Study of Paediatric Status Epilepticus in Emergency Departments of Australia and New Zealand. The Status Epilepticus Australasian Registry for Children (SEARCh)

Grant ID: EMSS-227R24-2015

Project Summary

Convulsive status epilepticus (CSE) occurs when seizures do not stop spontaneously. It is the most severe form of epilepsy, and can result in long-term disabilities and rarely death. It can affect both adults and children, although the causes and outcomes are different in these groups of patients. Treatments of patients with CSE are largely based on expert opinion rather than strong evidence, due to the difficult nature of conducting quality trials in patients with this relatively infrequent condition in the emergency setting. We will determine the incidence and causes of CSE in children in Australia and New Zealand and collect information on the type of seizure, duration, treatment and outcome to determine ways to improve the management of children with CSE.


The pilot registry enrolled 172 children from four geographically diverse hospitals. The majority of patients arrived by ambulance and had a history of prior seizures/epilepsy. Valuable data was gathered into the complexity of a very rare, and potentially life-threatening condition in children and significant insights were gained into both pre-hospital and emergency department management of this condition. The team plans to build on these foundations with further work in this area, including the scope for earlier treatment with both benzodiazepines and second line drugs.


Amount Awarded


Grant Scheme


Principal Investigator:
Dr Jeremy Furyk

Co Investigators:
Dr Stuart Dalziel
A/Prof Franz Babl
Dr Shane George
Dr Natalie Phillips

Associate Investigators:
Ms Sharon O'Brien


Collaborating Institutions

CONTACT US +61 7 3720 5700 info@emfoundation.org.au Suite 1B, Terraces, 19 Lang Parade, Milton Qld 4064