How are we treating severe childhood asthma in Australasia?

Grant ID: EMSS-273R27-2017

Lay Summary

Most children with asthma presenting to an emergency department (ED) are managed with inhaled medications and oral steroids. Infrequently, some children are very unwell, and require assistance with their breathing, or intravenous medication Currently, there is minimal information to guide clinicians on which treatment to choose for severe acute asthma. All have side-effects, and we do not know which is most effective. Studies from the UK and Australasia demonstrate significant variation in practice, although Australasian data is nearly 10 years out of date. When comparing treatments, it is important to determine whether or not they can reduce the risk of severe complications, or whether they make a difference in important treatment outcomes.

This project will allow us to determine current management practices for children with severe acute asthma and/or wheeze; how common severe acute asthma is and also how frequently complications of severe asthma occur; and understand where differences in therapy exist between states/regions. We will be looking at sites across Australia and New Zealand. Once complete, this project will provide important data to allow us to design future research to establish the best treatments for severe asthma.

EMF is funding the Queensland sites taking part in this Australasian trial. This study is being run by the PREDICT network. The Chief Investigatory is A/Prof Simon Craig. The study will include 18,000 children aged 1 – 18 years treated for asthma in the ED.


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Amount Awarded
$69,444


Program


Grant Scheme


Status
Active


Principal Investigator:
Dr Ben Lawton


Co Investigators:
Dr Simon Craig
A/Prof Ed Oakley
A/Prof Franz Babl
Professor Andis Graudins
Dr Stuart Dalziel
A/Prof Jeremy Furyk
Dr Natalie Phillips
Dr Shane George


Associate Investigators:
Dr Charmaine Gray
Prof Steve Margolis


Institution


Collaborating Institutions


Links

  • PREDICT network project page

  • CONTACT US +61 7 3720 5700 info@emfoundation.org.au 2/15 Lang Parade Milton Qld 4064