Critical Evaluation of a Targeted Point of Care ROTEM and Multiplate Guided Coagulation and Haemostasis Management Program in Severe Trauma and Critical Bleeding

Rapid assessment of impaired blood clotting in critically bleeding patients

Grant ID: EMSS-406R21-2014

Lay Summary

In this project, the team investigated how to assess and treat patients with clotting disorders as a result of trauma and severe bleeding.

Patients with severe trauma and critical bleeding have a high risk of death from haemorrhage and the complications e associated with large volume blood transfusion. The ability of the patient to form a blood clot will be assessed using a ROTEM/multiplate device. This device gives an in-depth assessment of the patient’s clotting and allows specific treatment to be targeted at specific clotting defects. Using this technology, the investigators hope to reduce the amount of bleeding in these cases and also reduce the amount of blood transfused to these patients. The project will implement a blood product transfusion program guided by the ROTEM/multiplate device.

Leveraged Funds

- Gold Coast Health Private Practice Fund: $9000
- In-kind: $70,000


Presented at approximately 19 Conferences nationally and internationally:
- Elizabeth Wake, poster presentation, Gold Coast Nursing and Midwifery Symposium 4-5th September 2015
- Megan Shuttleworth, Gold Coast Health and Medical Research Conference. December 2015.
- James Winearls, Use of ROTEM in Critically Bleeding Patients, National Blood Symposium, Brisbane 12TH June 2015:
- Don Campbell, Targeted Coagulation Management for Trauma Patients, National Blood Symposium, Brisbane 12TH June 2015:
- James Winearls, Targeted Haemostasis in Critical Bleeding , Bedside Critical Care Meeting, Cairns 29th-3rd October 2014:
- Queensland Trauma Symposium, Royal Brisbane & Women's Hospital 20th February 2015: Targeted Coagulation Management in Trauma [James Winearls]
- James Winearls, Application of ROTEM point of care testing in critical bleeding , Agentina Society Haematology Conference Buenos Aires 16-18 September
- James Winearls, Targeted Coagulation Management, Australian Trauama Society Conference Gold Coast 2-4th October 2015
- Point of Care Testing- an intensive care perspective [James Winearls], Haematology Society of Australia and New Zealand Convention Adelailade 18-21 Oct 2015:
- James Winearls, ROTEM in Trauma, RCPA Pathology Update 2016.
- Elizabeth Wake, Sarah Czuchwicki, Dianah Barkman, 2015. Gold Coast Health and Medical Research Conference. December 2015.
- James Winearls. TEM International Critical Bleeding Meeting Bangkok. Jan 2016.
- James Winearls, Royal College of Pathologists. Feb 2016.
- Karin Walters. WFCCN/ACCCN. April 2016


Amount Awarded


Grant Scheme


Principal Investigator:
Dr Donald Campbell

Co Investigators:
Dr James Winearls
Dr Andrew Bulmer
Dr David Pearson
Dr Indu Singh

Associate Investigators:
Prof John Fraser
Dr Michelle Bryson
Prof Gerben Keijzers
Dr Gregory Comadira


Collaborating Institutions


  • Channel 9_ 31 March 2015
  • EMF media release_ 31 March 2015
  • Gold Coast Health Research Project of the Year_ 27 November 2015
  • CONTACT US +61 7 3720 5700 2/15 Lang Parade Milton Qld 4064